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In vivo anterior chamber injection of RSL3 induced more severe lens nuclear opacity in a highly myopic mouse model, which could be partially ameliorated by ferroptosis and DDR2 inhibitors

In the case of GSAO, a reversible renal toxicity described in preclinical studies at the maximal tolerated dose was not observed in human during clinical Phase I (Horsley et al., 2013)

10.1016/j.jsxm.2019.09.017 37 KildegaardH.BliddalM.ErnstM

We are grateful to Xixia Li, and Xueke Tan for helping with electron microscopy sample preparation and taking TEM images at the Center for Biological Imaging (CBI), Institute of Biophysics, Chinese Academy of Science

Cholesterol is a lipid that is naturally found in human skin and is one of the three key components of your skin barrier